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AssigneeMassachusetts Institute of Technology
InventorsEric Schwoebel, James Harper, Martha S. Petrovick, Frances Nargi, Mark Hollis, Bernadette Johnson, Joseph Lacirignola, Richard Mathews, Kristine Hogan, Trina Vian, Allan Heff, Mark Hennessy, Songeeta Palchaudhuri, Todd Rider
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The invention described herein provides methods for the detection of target particles, such as pathogens, soluble antigens, nucleic acids, toxins, chemicals, plant pathogens, blood borne pathogens, bacteria, viruses and the like. Also described is an emittor cell comprising a receptor, wherein the receptor can be an antibody or an Fc receptor, and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more receptors on the emittor cell. Also provided are optoelectronic sensor devices for detecting a target particle in a sample, including in a plurality of samples.
A method for detecting a soluble antigen in a sample comprising:
A device for detecting a soluble antigen in a sample, wherein the antigen is bound by a receptor on an emittor cell, said emittor cell comprising a receptor and an emittor molecule that emits a photon in response to binding of a target antigen in the sample to the receptor, wherein the device detects the emission of the photon, thereby detecting a soluble antigen in a sample.
A method for detecting a target particle in an air sample comprising:
A device for detecting a target particle in an air sample comprising
A method to detect a plant pathogen comprising:
A method for detecting a pathogen in a clinical sample comprising:
Dependencies are inferred from the claim text.