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US 2009/0291964 A1Published application
Potentiators of Antibacterial Activity
AssigneeVertex Pharmaceuticals Incorporated
InventorTrudy Hope Grossman
Life of this patent
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Abstract
The present invention relates to compounds that potentiate the activity of antibacterials. The present invention also relates to compositions useful in treating bacterial infection in mammals, and methods therewith. The present invention also relates to a method of inhibiting bacterial efflux of an antibiotic, thereby increasing the efficacy of the antibiotic.
Claims13
1-31. (canceled)
A pharmaceutical composition comprising:
- (i) an antibiotic;
- and
- (ii) the compound:
- or a pharmaceutically acceptable salt thereof.
1 more element
(canceled)
Dependencies are inferred from the claim text.