Transdermal anti-dementia active agent formulations and methods for using the same
OwnerJianye Wen, Yoshiko Katoriinventors
Life of this patent
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Abstract
A transdermal antidementia active agent formulation is provided. In certain embodiments, the formulation includes a backing, an active agent reservoir layer including an antidementia active agent, wherein the antidementia active agent is present as both a freebase and optionally also present as a salt, an adhesive layer including the antidementia active agent, and optionally an adhesive overlay. Also provided are methods of using the formulations, e.g. for administering an antidementia active agent to a subject, and kits containing the formulations.
Claims29
A transdermal antidementia active agent formulation, said formulation comprising:
- a backing;
- an active agent reservoir layer comprising an antidementia active agent, wherein said antidementia active agent is present as a freebase;
- and
- an adhesive layer comprising said antidementia active agent.
A method for administering an antidementia active agent to a subject, said method comprising:
- (a) applying to a skin site of said subject a transdermal antidementia active agent formulation, said formulation comprising:
- (i) a backing;
- (ii) a polymeric active agent reservoir layer comprising an antidementia active agent, wherein said antidementia active agent is present as both a freebase and as a salt;
- and
- (iii) an adhesive layer comprising said antidementia active agent as freebase;
- and
- (b) maintaining said formulation at said skin site of said subject for a period of time sufficient to deliver said active agent to said subject.
26-46. (canceled)
A kit comprising a transdermal antidementia active agent formulation, said formulation comprising:
- a backing;
- an active agent reservoir layer comprising an antidementia active agent, wherein said antidementia active agent is present as a freebase;
- and
- an adhesive layer comprising said antidementia active agent.
49-69. (canceled)
Dependencies are inferred from the claim text.