Fab i inhibitors

A composition comprising:

• a compound according to formula (I):
• wherein:
• R1 is H or C1-4alkyl;
• R2 is H, C1-4alkyl or C3-6cycloalkyl;
• R3 is
• R4 is H or C1-4alkyl;
• indicates that one of the two designated bonds is a double bond and the other is a single bond;
• R5 is CH2 when the bond to which it is attached is a double bond;
• or R5 is H or C1-4 alkyl when the bond to which it is attached is a single bond;
• R6 is H or C1-4alkyl;
• R7 is H, C1-6alkyl or —C0-6alkyl-Ar;
• Y is H, C1-4alkyl, N(R′)2, NHC(O)R′, NHCH2C(O)R′ or NHC(O)CH═CHR′;
• each X independently is H, C1-4alkyl, CH2OH, OR′, SR′, CN, N(R′)2, CH2N(R′)2, NO2, CF3, CO2R′, CON(R′)2, COR′, NR′C(O)R′, F, Cl, Br, I or —S(O)rCF3;
• W is S or O;
• Q is H or C1-4alkyl;
• M is CH2 or O;
• L is CH2 or C(O);
• E is O or NR′;
• each R′ independently is H, C1-6alkyl or —C0-6alkyl-Ar;
• and
• r is 0, 1 or 2;
• or a pharmaceutically acceptable salt thereof;
• and
• a pharmaceutically acceptable excipient.