ANTIBODY DIRECTED AGAINST PAP2a AND USE THEREOF FOR DIAGNOSTIC AND THERAPEUTIC PURPOSES
AssigneeSapporo Medical University
InventorsHirofumi Hamada, Kiminori Nakamura, Kazunori Kato
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Abstract
The present invention aims at developing a gene delivery system which has a high selectivity to a target cell and can introduce and express a gene with high efficiency, particularly developing such a system for use in a gene delivery therapy using a viral vector. The present invention provides a method for targeting a drug, which comprises the step of delivering a drug containing a therapeutic gene to a target site using an anti-PAP2a antibody.
Claims27
A monoclonal antibody against PAP2a.
A diagnostic agent for cancer comprising an anti-PAP2a antibody.
A method for diagnosing cancer, which comprises the step of detecting and/or quantifying a PAP2a protein, its fragment, or a nucleic acid encoding the same, in a biological sample derived from a subject, as a diagnostic marker.
An agent for treating cancer comprising an anti-PAP2a antibody.
A method for targeting a drug, which comprises delivering a drug to a target site using an anti-PAP2a antibody.
Dependencies are inferred from the claim text.