Il-17 homologous polypeptides and therapeutic uses thereof
AssigneeGenentech, Inc.
InventorsJian CHEN, Ellen Filvaroff, Audrey Goddard, Austin Gurney, Hanzhong Li, William I. Wood
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AssigneeGenentech, Inc.
InventorsJian CHEN, Ellen Filvaroff, Audrey Goddard, Austin Gurney, Hanzhong Li, William I. Wood
Estimating the term…
The present invention is directed to novel polypeptides having sequence identity with IL-17 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders.
An isolated antibody that binds the polypeptide of SEQ ID NO:3.
An isolated antibody that binds the mature polypeptide of SEQ ID NO:3 consisting of amino acid residues 19-197 of SEQ ID NO:3.
An isolated antibody that binds the polypeptide encoded by the cDNA clone deposited as ATCC deposit number 203552.
Dependencies are inferred from the claim text.