Back to results
US 2008/0306246 A1Published application
Process for Attaching Effector Molecules to Proteins
AssigneeUCB Pharma S.A.
InventorSam Philip Heywood
Life of this patent
Estimating the term…
Abstract
The present invention provides a process for attaching one or more effector molecules to one or more cysteines in a protein comprising: a) activating one or more cysteines in the protein by diafiltering the protein against a monothiol reducing agent or a multi-thiol reducing agent which is incapable of forming intramolecular disulphide bonds and b) reacting the treated protein with an effector molecule.
Claims20
A process for attaching one or more effector molecules to one or more cysteines in a protein comprising:
- a) activating one or more cysteines in the protein by diafiltering the protein against a monothiol reducing agent or a multi-thiol reducing agent which is incapable of forming intramolecular disulphide bonds and
- b) reacting the treated protein with an effector molecule.
Dependencies are inferred from the claim text.