Stable non-aqueous pour-on compositions
AssigneeWyeth
InventorsJacob Allen Zupan, Robert Bruce Albright, Douglas Rugg, Izabela Galeska, Chungjian Jerry Ong
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Abstract
The present invention relates to a stable, antiparasitic, non-aqueous pour-on parasiticidal composition which comprises an effective amount of amitraz, optionally a macrocyclic lactone, a stabilizer and a carrier system having no active hydroxyl group.
Claims31
A veterinary parasiticidal composition comprising a non-hydroxyl-containing solvent, a stabilizer, and amitraz;
- wherein
- either (a) the composition comprises a macrocyclic lactone;
- or (b) said non-hydroxyl-containing solvent comprises:
- about 5% to about 20% w/v of an aromatic solvent;
- about 10% to about 75% w/v of caprylic/capric triglyceride or mineral oil or a combination thereof;
- and
- 0% to about 15% w/v isopropyl myristate;
- and
- provided that the composition is substantially free of hydroxyl-containing solvents.
A method for the treatment or control of a parasiticidal infection or infestation in a homeothermic animal which comprises topically administering to said animal a non-hydroxyl-containing solvent, a stabilizer, and amitraz;
- wherein
- either (a) the method further comprises administering a macrocyclic lactone;
- or (b) said non-hydroxyl-containing solvent comprises:
- about 5% to about 20% w/v of an aromatic solvent;
- about 10% to about 75% w/v of caprylic/capric triglyceride or mineral oil or a combination thereof;
- and
- 0% to about 15% w/v isopropyl myristate.
Dependencies are inferred from the claim text.