Back to results
US 2008/0305180 A1Published application
Method of administration of a pulmonary surfactant
AssigneeChiesi Farmaceutici S.p.A.
InventorsEgbert Herting, Wolfgang Gopel, Paolo Chiesi
Life of this patent
Estimating the term…
Abstract
The present invention concerns a method for treating a respiratory distress in a infant in need of such treatment, the method comprising intratracheal administration of a pulmonary surfactant by a thin tube. The invention also concerns a kit for performing said method.
Claims17
A method for treating a respiratory distress in an infant in need of such treatment, said method comprising the steps of:
- a) applying nasal Continuous Positive Airway Pressure (nCPAP) with a nasal device to said infant at a pressure of from 1 to 12 cm water;
- b) instillingadministering a pulmonary surfactant suspended in a pharmaceutically acceptable aqueous medium via a tube having a diameter comprised between 5 and 12 Fr into the trachea of said infant;
- and
- c) removing said tube
- wherein the surfactant suspension is applied at a concentration of at least 40 mg/ml and has a viscosity lower than 20 mPas.
2 more elements
A kit comprising:
- a) a sterile pharmaceutical composition comprising a pulmonary surfactant having a viscosity lower than 20 mPas suspended in a pharmaceutically acceptable aqueous medium at a concentration of at least 40 mg/ml;
- b) a tube having a diameter comprised between 5 and 12 Fr;
- c) a device for instillingadministering the surfactant at a controlled rate;
- d) container means for containing the dosage form, the gastric tube and the device.
1 more element
Dependencies are inferred from the claim text.