Mucoadhesive vesicles for drug delivery
OwnerThomas Hirt, Zhihue Lu +2inventors
InventorsThomas Hirt, Zhihue Lu, Wolfgang Meier, Mansoor Amiji
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Abstract
Vesicles for delivery of active macromolecules which are formed from amphiphilic segmented copolymers having one or more mucoadhesive groups or regions and which can be used for delivery of an active agent to an area of the body having a mucous membrane, such as but not limited to the gastrointestinal tract.
Claims24
A drug delivery vehicle, comprising mucoadhesive vesicles made from amphiphilic segmented copolymers having an AB, ABA, or ABC structure, wherein segments A and C are each hydrophilic, segment B is hydrophobic, and at least one segment is mucoadhesive.
An amphiphilic segmented copolymer for forming mucoadhesive drug delivery vesicles, having an AB, ABA, or ABC structure, wherein segments A and C are each hydrophilic, segment B is hydrophobic, and at least one segment is mucoadhesive.
Dependencies are inferred from the claim text.