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US 2008/0293769 A1Published application
Polymorphs of a C-Met/Hgfr Inhibitor
AssigneePfizer Inc.
InventorsJingrong Jean Cui, Michelle Bich Tran-Dube
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Abstract
This invention relates to polymorphs of (R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to compositions including such salts and polymorphs, and to methods of using such compositions in the treatment of abnormal cell growth in mammals, especially humans.
Claims17
A free base of (R)-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine as a crystalline form.
Dependencies are inferred from the claim text.