Use of Amino Acids for Making Medicines for Treating Insulin Resistance
AssigneeInnodia Inc.
InventorsGerard Ribes, Mohammed Taouis, Roger Pierre Petit, Christophe Broca, Yves Sauvaire, Bernard Pau
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Abstract
The invention concerns the use of monohydroxy or polyhydroxy amino acids, and the lactone forms thereof for making medicines with insulin-analogue and/or insulin-sensitizing effects on peripheral tissues targeted by insulin, and more particularly the use thereof for making medicines for treating and preventing insulin-resistance.
Claims14
1) Use of a compound chosen from the group constituted by mono-hydroxylated amino acids, poly-hydroxylated amino acids, and the lactonic forms of these acids, for the manufacture of a medicament with insulin mimetic and/or insulin-sensitizing effects.
4) Use according to any one of the previous claims, characterised in that said compound is 4-hydroxyisoleucine of formula
- and/or the lactonic form of this amino acid.
14) Pharmaceutical composition or kit comprising both insulin and a compound chosen from the group constituted by mono-hydroxylated amino acids, poly-hydroxylated amino acids, and the lactonic forms of these acids.
Dependencies are inferred from the claim text.