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OwnerKevin Hudson, Marie Caroline South +2inventors
InventorsKevin Hudson, Marie Caroline South, Gayle Marshall, Mehran Sam
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The invention relates to a method of selecting a mammal having or suspected of having a tumour for treatment with an erbB receptor drug which comprises testing a biological sample from the mammal for expression of anyone of the genes listed in Table 1 or 2 as defined herein whereby to predict an increased likelihood of response to the erbB receptor drug. Preferred genes include anyone of NES, GSPT2, ETR101, TAZ, CHST7, DNAJC3, NPAS2, PIN1, TCEA2, VAMP4, DAPK1, DAPK2, MLLT3, TNNC1, KIAA0931, ACOX2, EMP1, SLC20A1, SPRY2 or PGM1.
A method of selecting a mammal having or suspected of having a tumour for treatment with an erbB receptor drug which comprises testing a biological sample from the mammal for expression of any one of the genes listed in Table 1 or DAPK2, whereby to predict an increased likelihood of response to the erbB receptor drug.
Dependencies are inferred from the claim text.