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US 2008/0188823 A1Published application
Method for Delivering Interferon-Beta
AssigneeBiogen Idec MA Inc.
InventorsEric Anthony Faulkner, Mary Diana DiBiase
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Abstract
The method described herein reduces the amount of aggregating metal released into solutions of Interferon-β.
Claims53
A method for storing and delivering solutions of Interferon-β comprising:
- providing a device including a housing for retaining a solution of Interferon-β;
- filling the solution of Interferon-β into the housing, wherein, after filling the solution, the housing releases a concentration of an aggregating metal into the solution of less than 500 parts per billion.
A method for storing and delivering solutions of an Interferon-β comprising:
- providing a device including a housing for retaining a solution of Interferon-β;
- filling the solution of Interferon-β into the housing, wherein, after filling the solution, the housing releases a total concentration of aggregating metals into the solution of less than 500 parts per billion.
A method for storing and delivering solutions of Interferon-β comprising:
- providing a device including a housing for retaining a solution of Interferon-β;
- filling the solution of Interferon-β into the housing, wherein, after filling the solution, aggregation of Interferon-β caused by aggregating metals in the solution is less than 15% after storage.
A device comprising:
- a housing for retaining a solution;
- a solution of Interferon-β retained within the housing, wherein the housing releases a total concentration of aggregating metals into the Interferon-β solution of less than 500 parts per billion.
Dependencies are inferred from the claim text.