Insecticidal and Nematicidal Compositions and Methods of Use
OwnerJeffrey R. Bloomquist, Edwin E. Lewisinventors
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Abstract
The present invention provides methods of protecting plants and other multicellular organisms from the parasitic activity of nematodes and insects. The methods use compounds, such as stilbene compounds, as nematicidal and insecticidal compounds, which act to alter the activity of one or more anion transporters in the nematodes and insects. Methods of screening for such compounds are also provided.
Claims23
A method of treating a multicellular host organism attacked, bitten, infected, or parasitized by at least one nematode, at least one insect, at least one acarine, or combinations of two or all three of these, said method comprising contacting the host organism or its environment with at least one compound in amount sufficient to disrupt the activity of at least one anion transporter of the nematode, insect, or acarine, the disruption reducing the viability or activity of the nematode, insect, or acarine.
A method of protecting a multicellular host organism attacked, bitten, infected, or parasitized by at least one nematode, insect, or acarine, said method comprising contacting the nematode or insect or acarine with at least one compound in amount sufficient to disrupt the activity of at least one anion transporter of the nematode, insect, or acarine, the disruption reducing the activity or viability of the nematode or insect or acarine.
A method of identifying a test compound having nematicidal, insecticidal, or acaricidal activity, said method comprising:
- exposing at least one anion transporter from at least one nematode, insect, or Acari to at least one test compound,
- providing sufficient time for the anion transporter(s) and test compound(s) to come into contact;
- and
- determining whether one or more of the test compounds affected the activity of one or more of the anion transporters,
- wherein an effect on the activity of at least one anion transporter indicates nematicidal or insecticidal or acaricidal activity of at least one of the test compounds.
Dependencies are inferred from the claim text.