Methods of treating avian hypertension
AssigneesThe Regents of the University of California Office of Technology Transfer, Texas A&M University
InventorsBruce D. Hammock, Todd R. Harris, Christophe Morisseau, Rosemary L. Walzem
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Abstract
The present invention provides methods of treating avian pulmonary hypertension syndrome by administering to an avian subject a therapeutically effective amount of an inhibitor of soluble epoxide hydrolase (“sEHI”), alone or co-administered in combination with a cis-epoxyeicosantrienoic acid (“EET”). The invention also provides nucleic acid and amino acid sequences of an avian soluble epoxide hydrolase.
Claims12
A method of inhibiting or preventing pulmonary hypertension syndrome or a symptom thereof in an avian subject in need thereof, said method comprising administering to said avian subject an effective amount of an inhibitor of soluble epoxide hydrolase (“sEH”), thereby inhibiting pulmonary hypertension syndrome or said symptom thereof in said avian subject.
An isolated nucleic acid encoding a soluble epoxide hydrolase having at least 95% nucleic acid sequence identity to the nucleic acid sequence depicted in FIG. 1.
An isolated soluble epoxide hydrolase having at least 95% amino acid sequence identity to the amino acid sequence depicted in FIG. 1.
Dependencies are inferred from the claim text.