Compounds for the Treatment of Hepatitis C

A compound of formula I

• where:
• R1 is CO2R6 or CONR7R8;
• R2 is COR2, COCOR, SO2N(R14)(R15), or SO2R16;
• R3 is hydrogen or alkyl;
• R4 is hydrogen, halo, alkyl, alkenyl, hydroxy, benzyloxy, or alkoxy;
• R5 is cycloalkyl;
• R6 is hydrogen or alkyl;
• R7 is hydrogen, alkyl, alkylSO2, cycloalkylSO2, haloalkylSO2, (R9)2NSO2, or (R10)SO2;
• R8 is hydrogen or alkyl;
• R9 is hydrogen or alkyl;
• R10 is azetidinyl, pyrrolidinyl, piperidinyl, N—(R11)piperazinyl, morpholinyl, thiomorpholinyl, homopiperidinyl, N—(R11)homopiperazinyl, or homomorpholinyl;
• R11 is hydrogen or alkyl;
• and
• R12 is amino, alkylamino, or dialkylamino;
• or R12 is azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, homopiperidinyl, homopiperazinyl, or homomorpholinyl, and is substituted with 0-3 substituents selected from alkyl, alkoxy, and phenyl wherein phenyl is substituted with 0-3 substituents selected from cyano, halo, alkyl, and alkoxy;
• or R12 is
• R13 is hydroxy, alkoxy, amino, alkylamino, or dialkylamino;
• or R13 is azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, homopiperidinyl, homopiperazinyl, or homomorpholinyl, and is substituted with 0-3 substituents selected from alkyl, alkoxy, and phenyl wherein phenyl is substituted with 0-3 substituents selected from cyano, halo, alkyl, and alkoxy;
• or R13 is
• R14 is hydrogen, or alkyl;
• R15 is hydrogen or alkyl;
• R16 is alkyl, cycloalkyl, or haloalkyl;
• or R16 is azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, morpholinyl, thiomorpholinyl, homopiperidinyl, homopiperazinyl, or homomorpholinyl, and is substituted with 0-3 substituents selected from alkyl, alkylcarbonyl, alkoxycarbonyl, benzyl, and benzyloxycarbonyl;
• or R16 is phenyl substituted with 0-3 substituents selected from cyano, halo, alkyl, haloalkyl, alkoxy, and haloalkoxy;
• R17 is hydrogen, alkyl, cycloalkyl, (cycloalkyl)alkyl, benzyl, alkylcarbonyl, alkoxycarbonyl, benzyloxycarbonyl, alkylSO2, or pyridinyl;
• and
• X is absent, a bond, or methylene;
• or a pharmaceutically acceptable salt thereof.