Virus-Interacting Layered Phyllosilicates and Methods of Use
AssigneeAMCOL International Corporation
InventorsJerald W. Darlington, John Hughes, Panayiotis P. Constantinides, Mingming Fang, Jason H. St. Onge
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Abstract
Layered phyllosilicates are useful for adsorbing and/or binding to and, thereby, inactivating viruses. Accordingly, provided herein are methods of inactivating a virus and methods of treating a viral infection. Methods of delivering a therapeutic agent to a mammalian subject and methods of inactivating a virus in the gastrointestinal tract of an animal are also provided.
Claims69
A method of inactivating a virus comprising contacting a virus with a composition comprising a hydrogen protonated layered phyllosilicate material in an amount effective for virus inactivation.
A method of treating a viral infection in a subject, the method comprising administering to said subject a composition comprising a hydrogen protonated layered phyllosilicate material and a pharmaceutically acceptable carrier in an amount effective to treat said viral infection.
A method of treating a viral infection in a subject in need of treatment comprising administering to a subject in need thereof a therapeutically effective amount of a combination therapy comprising (a) a layered phyllosilicate material and (b) a therapeutic agent.
A method of inhibiting transfer of a virus to a surface, the method comprising contacting the surface with a composition comprising a hydrogen protonated layered phyllosilicate material in an amount sufficient for inhibiting the transfer of the virus thereto.
A method of promoting wound healing in a subject in need thereof comprising administering to said subject a therapeutically effective amount of a composition comprising a layered phyllosilicate material and a pharmaceutically acceptable carrier, diluent or excipient.
A patch comprising a pad material having an upper surface and lower surface, an adhesive on the lower surface, and a therapeutic composition, wherein the therapeutic composition comprises a layered phyllosilicate material.
A surgical suturing thread coated or impregnated with a composition, wherein said composition comprises a layered phyllosilicate material.
A method of promoting the absorption of a therapeutic agent through the mucosal membranes in a mammalian subject, comprising administering to said subject a composition comprising a therapeutic agent, a layered phyllosilicate material and pharmaceutically acceptable carrier, diluent or excipient.
A method of delivering a diagnostic agent to a biological fluid or a subject comprising administering a composition comprising a diagnostic agent and a layered phyllosilicate material.
Dependencies are inferred from the claim text.