Multi-portion endoluminal prosthesis

An endoluminal prosthesis comprising:

• a tube having a first portion comprising a first tubular graft material being non-porous and non-bioabsorbable and a second portion comprising a second tubular graft material being bioabsorbable, wherein the first and second portions are arranged coaxially in series and coupled to one another, wherein second tubular graft material comprises at least one of polyglactin, polyglycolic acid, polyglyconate, polydioxanone and a copolymer of a glycolide and lactide;
• an expandable stent coupled to the tube, wherein the stent comprises a plurality of self-expanding stent elements that are coupled along a length of the first portion of the tube;
• a second stent coupled to the second portion of the tube, wherein the second stent comprises a plurality of self-expanding stent elements that are coupled along a length of the second portion of the tube;
• wherein the second tubular graft material is porous, wherein the porous material comprises a derived collagen material, wherein the derived collagen material is an extracellular matrix, wherein the extracellular matrix is small intestinal submucosa, stomach submucosa, pericardium, liver basement membrane, or urinary bladder submucosa, and
• wherein the first portion of the tube comprises a synthetic material, wherein the synthetic material is a polyester, polytetrafluoroethylene, or expanded polytetrafluoroethylene.