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AssigneesKent State University, University of Chester
InventorsNicola Brasch, Catherine Birch, John Williams
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Therapeutic applications, such as prevention, treatment and supplementation, for the use of novel and other thiolatocobalamins to protect human cells against the effects of oxidative stress. In particular, this invention relates to the use of a novel synthetic thiolatocobalamin, N-acetyl-L-cysteinylcobalamin (NACCbl) to protect animal cells against oxidative stress damage. This invention also relates to the use of thiolatocobalamins, such as NACCbl, in lieu of current, commercially available forms of vitamin B12 for the treatment and prevention of conditions associated with oxidative stress damage and for dietary supplementation.
A method to treat, ameliorate or prevent a disease associated with or a condition of oxidative stress in an animal comprising administering an effective amount of N-acetyl-L-cysteinylcobalamin.
A method of reducing high homocysteine levels or of reducing free radical formation levels in an animal comprising administering an effective amount of N-acetyl-L-cysteinylcobalamin.
A pharmaceutical composition comprising N-acetyl-L-cysteinylcobalamin.
A dietary supplement comprising N-acetyl-L-cysteinylcobalamin.
Dependencies are inferred from the claim text.