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OwnerKwee-Hyun SUH, Gi-Jeong Kim +3inventors
InventorsKwee-Hyun SUH, Gi-Jeong Kim, Sang-Min Yoon, Mi-Ra Seong, Gwan-Sun Lee
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The present invention relates to a clathrate of azithromycin hydrate with 1,2-propyleneglycol of formula (I), a method for the manufacture thereof, and a pharmaceutical composition containing same. The inventive compound is much less hygroscopic than azithromycin hydrate or crystals known in the art, therefore, it can be useful for the preparation of a medicine for treating various microbial infections. wherein m ranges from 1 to 2 and n, from 0.30 to 0.45.
1-7. (canceled)
A non-aqueous pharmaceutical composition for treating bacterial infection, comprising a clathrate compound of azithromycin hydrate with 1,2-propyleneglycol of formula (I) and a pharmaceutically acceptable carrier:
Dependencies are inferred from the claim text.