L-cysteine-producing microorganism and a method for producing L-cysteine
OwnerHiroshi Takagi, Shigeru Nakamori +2inventors
InventorsHiroshi Takagi, Shigeru Nakamori, Masaru Wada, Hirotada Mori
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Abstract
L-cysteine is produced by culturing an Escherichia bacterium having L-cysteine producing ability and containing a gene encoding an O-acetylserine sulphydrylase B or MalY regulatory protein that is modified so that cysteine desulfhydrase activity is reduced or eliminated. The bacterium is cultured in a medium to produce and cause accumulation of L-cysteine in the medium, and collecting L-cysteine from the medium.
Claims12
An Escherichia bacterium having L-cysteine-producing ability, wherein said bacterium contains a gene encoding O-acetylserine sulphydrylase B, and wherein said gene is modified so that cysteine desulfhydrase activity is reduced or eliminated.
An Escherichia bacterium having L-cysteine producing ability, wherein said bacterium contains a gene encoding MalY regulatory protein, and wherein said gene is modified so that cysteine desulfhydrase activity is reduced or eliminated.
Dependencies are inferred from the claim text.