Topical Pharmaceutical Compositions Containing An Antiacne Compound And Antibiotic Compound
AssigneeGlenmark Pharmaceuticals S.A.
InventorsGhanshyam Chaudhari, Vasant Khachane, Nitin Bhamre, Jagannath Macharla
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Abstract
Pharmaceutical compositions suitable for the treatment of skin disorder are provided which include at least a therapeutically effective amount of at least on antiacne agent and at least one antibiotic agent as active pharmaceutical ingredients and a hydrophilic matrix capable of providing a constant and uniform release of the active pharmaceutical ingredients.
Claims28
A topical pharmaceutical composition comprising (a) a therapeutically effective amount of adapalene or a pharmaceutically acceptable salt or ester thereof;
- (b) clindamycin or a pharmaceutically acceptable salt or ester thereof:
- and (c) a hydrophilic matrix capable of providing a constant and uniform release of the active pharmaceutical ingredients.
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A process for preparing a topical pharmaceutical composition comprising (a) preparing a drug dispersion phase comprising a therapeutically effective amount of at least one or more antiacne agent(s);
- (b) preparing a solution comprising a therapeutically effective amount of one or more antibiotic agents;
- (c) preparing a hydrophilic matrix phase capable of providing a constant and uniform release of the at least one antiacne agent and at least one antibiotic agent;
- and (d) mixing components (a)-(c) to form a topical pharmaceutical composition.
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Dependencies are inferred from the claim text.