Stabilized Calcium Phosphate Complexes
AssigneeThe University of Melbourne
InventorEric Reynolds
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Abstract
The present invention relates to a phosphopeptide-stabilized amorphous calcium phosphate and/or amorphous calcium fluoride phosphate complex, wherein the complex is formed at a pH of below 7.0. Methods of making such complexes are also provided. The complexes are useful in dental applications, in particular in dental remineralisation.
Claims20
A phosphopeptide stabilised amorphous calcium phosphate (ACP) or amorphous calcium fluoride (ACFP) complex, wherein the complex is formed at a pH of 7.0 or below, and wherein the ACP or ACFP is predominantly in a basic form.
A method of producing a phosphopeptide stabilised amorphous calcium phosphate (ACP) complex comprising the steps of
- (i) obtaining a solution comprising at least one phosphopeptide and;
- (ii) admixing solutions comprising calcium ions, phosphate ions and hydroxide ions while maintaining the pH at about 7.0 or below.
A method of producing a phosphopeptide stabilised amorphous calcium fluoride phosphate (ACFP) complex comprising the steps of
- (i) obtaining a solution comprising at least one phosphopeptide and;
- (ii) admixing solutions comprising calcium ions, phosphate ions and hydroxide ions while maintaining the pH at about 7.0 or below.
-25. (canceled)
Dependencies are inferred from the claim text.