Methods of treatment with an antibody that suppresses growth differentiation factor-14 activity
AssigneeThe Johns Hopkins University School of Medicine
InventorsSe-Jin Lee, Christopher Rankin
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Abstract
Growth differentiation factor-14 (GDF-14) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-14 polypeptide and polynucleotide sequences.
Claims20
A method of treating an immunologic disorder associated with expression of GDF-14 in a subject, comprising contacting cells expressing GDF-14 with a reagent that suppresses or enhances GDF-14 expression.
A method of treating cancer in a subject, comprising contacting cells expressing GDF-14 with a reagent that suppresses or enhances GDF-14 expression.
Dependencies are inferred from the claim text.