Delivery of stimulants through an inhalation route

A composition for delivery of fenfluramine consisting of a condensation aerosol

• a. formed by volatilizing a coating of fenfluramine on a solid support, having the surface texture of a metal foil, to a temperature sufficient to produce a heated vapor of fenfluramine and condensing the heated vapor of fenfluramine to form condensation aerosol particles,
• b. wherein said condensation aerosol particles are characterized by less than 5% fenfluramine degradation products, and
• c. the condensation aerosol has an MMAD of less than 3 microns.

A method of producing ephedrine in an aerosol form comprising:

• a. heating a coating of ephedrine on a solid support, having the surface texture of a metal foil, to a temperature sufficient to volatilize the ephedrine to form a heated vapor of the ephedrine, and
• b. during said heating, passing air through the heated vapor to produce aerosol particles of the ephedrine comprising less than 5% ephedrine degradation products, and an aerosol having an MMAD of less than 3 microns.

A method of producing fenfluramine in an aerosol form comprising:

• a. heating a coating of fenfluramine on a solid support, having the surface texture of a metal foil, to a temperature sufficient to volatilize the fenfluramine to form a heated vapor of the fenfluramine, and
• b. during said heating, passing air through the heated vapor to produce aerosol particles of the fenfluramine comprising less than 5% fenfluramine degradation products, and an aerosol having an MMAD of less than 3 microns.