Mutant protein and refolding method
OwnerRalph Biemans, Philippe Denoel +6inventors
InventorsRalph Biemans, Philippe Denoel, Christiane Feron, Karine Larine Goraj, Jeroen Kortekaas, Jan Poolman, Johannes Tommassen, Vincent Weynants
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Abstract
An FrpB protein having one or more deletions of non-conserved amino acids compared to a corresponding wild-type FrpB protein, and a method of refolding an FrpB protein.
Claims63
An FrpB protein having one or more deletions of non-conserved amino acids compared to a corresponding wild-type FrpB protein.
An FrpB protein in which one or more of the amino acids of at least one of its loops has been deleted.
A method for refolding an FrpB protein comprising contacting the FrpB protein with an alkaline refolding buffer comprising 3-dimethyldodecylammoniopropanesulfonate (Zwittergent 3-12 or SB-12).
Dependencies are inferred from the claim text.