Protein having PDZ domain sequence
AssigneeChugai Seiyaku Kabushiki Kaisha, a Japanese corporation
InventorsShin-Ichi Funahashi, Shoji Miyata
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Abstract
While analyzing changes in gene expression by TNFα in human umbilical vascular endothelial cells, a gene showing enhanced expression due to stimulation with TNFα was isolated. After screening with this gene as a probe, a gene encoding a protein was isolated. Analysis of the protein encoded by this isolated gene revealed that this novel protein has never been reported and has a PDZ domain in its molecule that plays an important role in protein-protein interactions.
Claims13
1-34. (canceled)
A substantially pure polypeptide comprising the amino acid sequence of SEQ ID NO:82.
A substantially pure polypeptide comprising the amino acid sequence of SEQ ID NO:83.
A substantially pure polypeptide comprising the amino acid sequence of SEQ ID NO:
- 84.
Dependencies are inferred from the claim text.