Nanoparticles for the administration of active ingredients, method of producing said particles and composition containing same
OwnerMaria Jose Fernandez, Carmen Remunan Lopez +2inventors
InventorsMaria Jose Fernandez, Carmen Remunan Lopez, Maria Margarita Cuna Vilan, Maria Alonso Sande
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Abstract
The invention relates to nanoparticles used for the administration of active ingredients, the method of producing said nanoparticles and compositions containing same. The inventive nanoparticles comprise a chitosan, glucomannan, at least one active ingredient and, if necessary, an anionic salt, preferably in sodium tripolyphosphate form. Said nanoparticles can be used to administer active ingredients to a human or animal body.
Claims29
A method of producing nanoparticles, with a mean diameter equal to or less than 1 m, and incorporating at least one active ingredient, comprising the following steps:
- a) preparing an aqueous chitosan solution,
- b) preparing an aqueous glucomannan solution, and
- c) mixing, under stirring, the solutions of steps a) and b), such that the chitosan and glucomannan nanoparticles are obtained,
- wherein at least one of the solutions of steps a) and b) contains at least one active ingredient.
Nanoparticles with a diameter equal to or less than 1 μm, for the administration of at least one active ingredient, comprising chitosan, glucomannan and at least one active ingredient.
Dependencies are inferred from the claim text.