Back to results
US 2006/0134214 A1Published application
Enteric coated bead comprising epothilone or epothilone analog, and preparation and administration thereof
OwnerIsmat Ullah, Gary Wileyinventors
Life of this patent
Estimating the term…
Abstract
Disclosed is an enteric coated bead comprising at least one epothilone or epothilone analog; and a capsule comprising a multitude of the enteric coated beads. Also disclosed are a method of preparing the enteric coated bead and a method of treating cancer or other proliferative diseases using the enteric coated bead.
Claims31
An enteric coated bead comprising:
- a) coated particle comprising:
- i) a base particle;
- and
- ii) an active ingredient layer disposed on said base particle, wherein said active ingredient layer comprises:
- 1) at least one epothilone or epothilone analog, or a pharmaceutically acceptable salt, solvate, clathrate, hydrate, or prodrug thereof;
- and
- 2) at least one binder;
- and
- b) an enteric coating encapsulating said coated particle.
6 more elements
A process for preparing enteric coated beads, comprising:
- a) providing base particles;
- b) applying an active ingredient mixture and binder to said base particles, wherein said active ingredient mixture comprises:
- i) at least one epothilone or epothilone analog, or a pharmaceutically acceptable salt, solvate, clathrate, hydrate, or prodrug thereof, and
- ii) solvent, water, or a mixture thereof;
- c) drying said base particles having application of said active ingredient mixture to provide coated particles;
- and
- d) applying an enteric coating to said coated particles to provide said enteric coated beads.
4 more elements
Dependencies are inferred from the claim text.