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US 2006/0078609 A1Published application
Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water soluble and respectively base
AssigneeJanssen Pharmaceutica NV
InventorsRoger Vandecruys, Jozef Peeters, Marcus Brewster
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Abstract
The invention provides a novel pharmaceutical composition comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base characterized in that the acid respectively base:drug compound ratio is at least 1:1 by weight.
Claims20
A pharmaceutical composition comprising a basic drug compound, a surfactant and a physiologically tolerable water-soluble acid characterized in that the acid:drug compound ratio is at least 1:1 by weight;
- or
- comprising an acidic drug compound, a surfactant and a physiologically tolerable water-soluble base characterized in that the base:drug compound ratio is at least 1:1 by weight.
A composition according to 6 wherein the polymer is selected from the group consisting of
- alkylcellulose,
- hydroxyakylcellulose,
- hydroxyalkyl alkylcellulose,
- carboxyalkylcellulose,
- alkali metal salts of carboxyalkylcelluloses,
- carboxyalkylalkylcelluloses,
- carboxyalkylcellulose esters,
- starches,
- pectins,
- chitin derivates,
- heparin, heparinoids,
- polysaccharides,
- polyacrylic acids and the salts thereof,
- polymethacrylic acids and the salts thereof, methacrylate copolymers,
- polyvinylalcohol,
- polyvinylpyrrolidone, copolymers of polyvinylpyrrolidone with vinyl acetate, and
- polyalkylene oxides.
14 more elements
Dependencies are inferred from the claim text.