In situ excitation for surface enhanced Raman Spectroscopy
AssigneeHewlett-Packard Development Company, L.P.
InventorsShih-Yuan Wang, Zhiyong Li, M. Islam
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Abstract
Devices, systems, and methods using Surface Enhanced Raman Spectroscopy (SERS) are disclosed. A device for generating Raman scattered radiation comprises a laser source and a SERS-active structure. The laser source may be configured for emanating radiation from an emanating surface or by forming a depression in the laser source, which creates a region of increased evanescent field from the laser source. SERS systems and methods include a device for generating Raman scattered radiation with a detector configured to receive the Raman scattered radiation.
Claims42
A molecular analysis device, comprising:
- a laser source configured for emanating a laser radiation from an emanating surface of the laser source;
- and
- a SERS-active structure disposed on the emanating surface and configured to produce a Raman scattered radiation when the laser radiation irradiates an analyte disposed on the SERS-active structure.
A molecular analysis device, comprising:
- a laser source having a depression formed in the laser source exposing a region of increased evanescent field generated when the laser source is active;
- and
- a SERS-active structure disposed in the depression and configured to produce a Raman scattered radiation when the evanescent field irradiates an analyte disposed on the SERS-active structure.
A surface enhanced Raman spectroscopy (SERS) system, comprising:
- a molecular analysis device, comprising:
- a laser source configured for emanating a laser radiation from an emanating surface of the laser source;
- and
- a SERS-active structure disposed on the emanating surface and configured to produce a Raman scattered radiation when the laser radiation irradiates an analyte disposed on the SERS-active structure;
- and
- a detector configured and positioned to receive the Raman scattered radiation.
A surface enhanced Raman spectroscopy (SERS) system, comprising:
- a molecular analysis device, comprising:
- a laser source having a depression formed in the laser source exposing a region of increased evanescent field generated when the laser source is active;
- and
- a SERS-active structure disposed in the depression and configured to produce a Raman scattered radiation when the evanescent field irradiates an analyte disposed on the SERS-active structure;
- and
- a detector configured and positioned to receive the Raman scattered radiation.
A method of performing surface enhanced Raman spectroscopy (SERS), comprising:
- providing a laser source configured for emanating a laser radiation from an emanating surface on the laser source;
- providing a SERS-active structure disposed on the emanating surface and configured such that the laser radiation irradiates the SERS-active structure;
- disposing an analyte over at least a portion of the SERS-active structure;
- irradiating the analyte and the SERS-active structure with the laser radiation to generate a Raman scattered radiation;
- and
- detecting the Raman scattered radiation.
A method of performing surface enhanced Raman spectroscopy (SERS), comprising:
- providing a laser source configured with a depression formed in the laser source at a region of increased evanescent field generated by the laser source;
- providing a SERS-active structure disposed in the depression and configured such that the evanescent field irradiates the SERS-active structure;
- disposing an analyte over at least a portion of the SERS-active structure;
- irradiating the analyte and the SERS-active structure with the evanescent field to generate a Raman scattered radiation;
- and
- detecting the Raman scattered radiation.
A method of performing surface enhanced Raman spectroscopy (SERS), comprising:
- providing a molecular analysis device comprising:
- a laser source configured for emanating a laser radiation from an emanating surface of the laser source;
- and
- a SERS-active structure disposed on the emanating surface;
- disposing an analyte over at least a portion of the SERS-active structure;
- irradiating the analyte and the SERS-active structure with the laser radiation to generate a Raman scattered radiation;
- and
- detecting the Raman scattered radiation.
A method of performing surface enhanced Raman spectroscopy (SERS), comprising:
- providing a molecular analysis device, comprising:
- a laser source having a depression formed in the laser source exposing a region of increased evanescent field generated when the laser source is active;
- and
- a SERS-active structure disposed in the depression;
- disposing an analyte over at least a portion of the SERS-active structure;
- and
- irradiating the analyte and the SERS-active structure with the evanescent field to generate a Raman scattered radiation;
- and
- detecting the Raman scattered radiation.
Dependencies are inferred from the claim text.