US 2006/0068401 A1 · Biopolymer resonant tunneling with a gate voltage source

Abstract

The invention provides an apparatus and method for sequencing and identifying a biopolymer. The invention provides a first electrode, a second electrode, a first gate electrode, a second gate electrode, a gate voltage source and a potential means. The gate electrodes may be ramped by a voltage source to search and determine a resonance level between the first electrode, biopolymer and second electrode. The potential means that is in electrical connection with the first electrode and the second electrode is maintained at a fixed voltage. A method of biopolymer sequencing and identification is also disclosed.

Claims20

Dependent claims

An apparatus for detecting a biopolymer in a nanopore, comprising:

(a) a first ring electrode;
(b) a second ring electrode adjacent to the first ring electrode;
(c) a first gate electrode in electrical connection with the first ring electrode and the second ring electrode for scanning the energy spectrum of the biopolymer;
(d) a second gate electrode in electrical connection with the first ring electrode and the second ring electrode for scanning the energy spectrum of the biopolymer;
(e) a nanopore adjacent to the first ring electrode and the second ring electrode and positioned to allow the biopolymer to be positioned in the first ring electrode and the second ring electrode;
(f) potential means in electrical connection with the first ring electrode and the second ring electrode for applying a fixed potential from the first ring electrode, through a portion of the biopolymer in the nanopore, to the second ring electrode to produce a signal indicative of the portion of the biopolymer;
and
(g) a gate voltage source in electrical connection with the first gate electrode and the second gate electrode for applying a ramped voltage to the first gate electrode and the second gate electrode.

5 more elements

Dependencies are inferred from the claim text.

Biopolymer resonant tunneling with a gate voltage source

Life of this patent

Biopolymer resonant tunneling with a gate voltage source

Life of this patent

Abstract

Claims20