Process for preparing poly (vinyl alcohol) drug delivery devices with humidity control

A process for making drug delivery devices, the process comprising the steps of:

• (a) providing a therapeutically active agent in a first part and a second part;
• (b) providing uncured poly(vinyl alcohol) in a first portion and a second portion;
• (c) curing the first portion of poly(vinyl alcohol) and second portion of poly(vinyl alcohol), wherein the first portion and the second portion are separated by a predetermined distance for a time period, wherein the humidity proximate the first portion and the second portion varies by a maximum of 30% points relative humidity;
• and
• (d) combining the first portion of poly(vinyl alcohol) and a second portion of poly(vinyl alcohol) with the respective first part and the second part in a respective first drug delivery device and a second drug delivery device.

A process for making a plurality of drug delivery devices, the process comprising the steps of:

• (a) providing a plurality of amounts of therapeutically active agent
• (b) providing a plurality of portions of poly(vinyl alcohol);
• (c) curing the plurality of portions that are separated by a predetermined distance for a time period, wherein the humidity proximate any one of the plurality of portions vary from any other of the plurality of portions by a maximum of 30% points relative humidity;
• and
• (d) combining the plurality of amounts of therapeutically active agent with the plurality of portions of poly(vinyl alcohol) to form a plurality of drug delivery devices.