Contact lens with improved biocidal activity and related methods and materials
AssigneeBausch & Lomb Incorporated
InventorErning Xia
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Abstract
The present invention is directed to a contact lens comprising a porous lens material and a disinfectant, including but not limited to domiphen bromide. The disinfectant is typically absorbed into the pores of the lens. The present invention also includes a related process for manufacture, method of use and kit.
Claims57
A contact lens comprising a porous lens material and a disinfectant, wherein weight of disinfectant in the porous lens material is a minimum of about 0.0001 μg of disinfectant and a maximum of about 100 μg of disinfectant for every mg of dry porous lens material.
The contact lens of claim 6, wherein the concentration of domiphen bromide in the porous lens material is a minimum of about 0.0001 μg of domiphen bromide and a maximum of about 10 μg of domiphen bromide for every mg of dry porous lens material.
A contact lens comprising a porous lens material and a disinfectant within pores in the porous lens material, wherein the contact lens releases at a minimum rate of about 10 ng/day and a maximum rate of about 200 ng/day.
A kit comprising a vessel that contains an aqueous solution of a domiphen salt and a contact lens made from a porous lens material.
A process for manufacturing a contact lens comprising the steps of
- forming the contact lens from a porous lens material;
- placing the lens in a solution of a domiphen salt.
A process for killing microbes on the surface of the eye comprising the step of releasing a disinfectant into the eye from pores of a contact lens made of a porous material in a therapeutically effective amount over a minimum period of one week.
A contact lens comprising a porous lens material and a therapeutically active agent, wherein the disinfectant is released in a therapeutically effective amount over a minimum period of one week.
A process for killing microbes on the surface of the eye comprising the step of releasing a therapeutic agent into the eye from the pores of a contact lens in a therapeutically effective amount over a minimum of one week.
Dependencies are inferred from the claim text.