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US 2006/0067939 A1Published application
Nanotubes for cancer therapy and diagnostics
AssigneesSecretary, Department of Health and Human Services, Board of Trustees of the University of Arkansas
InventorsDan Buzatu, Jon Wilkes, Dwight Miller, Jerry Darsey, Tom Heinze, Alex Biris, Richard Berger, Mark Diggs
Life of this patent
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Abstract
The present invention provides a novel approach to cancer therapy and diagnostics that utilizes nanotubes and other similar nanostructures as both an indirect source of radiation therapy (BNCT), and as delivery vehicles for other types of radio- and chemo-therapeutic materials, as well as imaging agents for diagnostic purposes.
Claims20
A method comprising:
- a) attaching a first antibody species to nanovessels to form nanovessel-antibody composite species;
- b) introducing said nanovessel-antibody composite species into a mammal such that they can selectively target cancerous cells;
- and
- c) using ultrasonic waves to explode the nanovessels.
1 more element
A method comprising:
- a) attaching a first IgG species to BN nanotubes to form BN nanotube-IgG composite species;
- b) administering said BN nanotube-IgG composite species to a mammalian subject such that the BN nanotube-IgG composite species targets tumors within said subject;
- and
- c) activating at least some of the boron atoms in the BN nanotube-IgG composite species;
- d) attaching radioactive isotopes to carbon nanotubes to form radioactive-laden carbon nanotubes;
- e) attaching a second IgG species to said radioactive-laden carbon nanotubes to form radioactive-laden carbon nanotube-IgG species;
- and
- f) introducing said radioactive-laden carbon nanotube-IgG species into the mammal.
- g) attaching a third IgG species to a nanovessels to form a nanovessel-IgG composite species;
- h) introducing said nanovessel-IgG composite species into a mammal such that they can selectively target cancerous cells;
- and
- i) using ultrasonic waves to explode the nanovessels.
9 more elements
Dependencies are inferred from the claim text.