Antifungal nail coat and method of use

A two-coat type, dual action, antifungal nail coat composition comprising:

• a first antifungal coat composition containing an effective fungicidal amount of antifungal agent dispersed in a pharmacologically tolerable, volatile organic carrier;
• and
• a second antifungal nail coat composition containing a film forming amount of hydrophilic polymer, an effective fungicidal amount of antifungal agent, and a pharmaceutically acceptable, volatile organic carrier,
• wherein either one of the first or second antifungal nail coat composition optionally includes a substantially non-volatile permeation enhancer, and
• wherein the first antifungal nail coat composition provides a fungicidal primer coat on a fungally-susceptible or infected nail on contact therewith, and the second antifungal nail coat composition provides a fungicidal film coat on the antifungal primer-coated nail on subsequent contact therewith.

A dual action antifungal nail coat composition comprising, on a total composition weight basis:

• about 0.5 to about 10 weight percent terbinafine hydrochloride;
• about 0.1 to about 10 weight percent dodecyl-2-(N,N-dimethylamino) isopropionate hydrochloride;
• about 0.1 to about 10 weight percent benzyl alcohol;
• about 0.1 to about 5 weight percent polyvinylpyrrolidone;
• and ethanol comprising the remainder.