Method of cell growth inhibition with agnoprotein
AssigneeTemple University of the Commonwealth System of Higher Education
InventorKamel Khalili
Life of this patent
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Abstract
The growth of normal and abnormally proliferating cells can be inhibited by the introduction of agnoprotein, or biologically active fragments or derivatives of agnoprotein, into the cell in the absence of any other polyoma virus protein or viral replication.
Claims27
A method of inhibiting cell growth comprising introducing into a cell an effective amount of one or more agnoproteins, or one or more biologically active fragments or derivatives of agnoprotein, such that growth of the cell is inhibited.
A method of treating a subject having a cancer or non-cancerous proliferative disorder, comprising administering to the subject an effective amount of one or more agnoproteins, or one or more biologically active fragments or derivatives of agnoprotein, such that growth of the cells deriving from the cancer or non-cancerous cells is inhibited.
A pharmaceutical composition comprising agnoprotein, or a biologically active fragment or derivative of agnoprotein and a pharmaceutically acceptable carrier.
A pharmaceutical composition comprising a nucleic acid sequence encoding agnoprotein, or a biologically active fragment or derivative of agnoprotein, and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.