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US 2006/0040364 A1Published application
DNA coding for a protein which imparts L-homoserine resistance to Escherichia coli bacterium, and a method for producing L-amino acids
OwnerVitaly Livshits, Natalia Zakataeva +3inventors
InventorsVitaly Livshits, Natalia Zakataeva, Vladimir Aleshin, Alla Belareva, Irina Tokmakova
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Abstract
A bacterium which has an ability to produce an amino acid and in which a novel rhtB gene encodes a protein having an activity of making a bacterium having the protein L-homoserine-resistant is enhanced, is cultivated in a culture medium to produce and cause accumulation of the amino acid in the medium, and the amino acid is recovered from the medium.
Claims9
An isolated DNA encoding an RhtB protein selected from the group consisting of:
- A) a protein comprising the amino acid sequence of SEQ ID NO:
- 2;
- and
- B) a protein variant which is at least 80% homologous to the amino acid sequence of SEQ ID NO:
- 2 and imparts resistance to L-homoserine to a bacterium which expresses said protein variant.
2 more elements
The bacterium of clam 5, wherein said DNA is present on a transposon in said bacterium.
Dependencies are inferred from the claim text.