Method and apparatus for magnetic sensing and control of reagents
OwnerAlison Chaiken, Manish Sharmainventors
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Abstract
An apparatus for characterizing reactions including a spinnable medium with one or more internal chambers capable of containing one or more reagents, a composite reagent that includes a magnetic component, a rotating mechanism capable of turning the spinnable medium, and a reading mechanism capable of measuring the magnetic component at one or more regions of the spinnable medium.
Claims26
An apparatus for characterizing reactions comprising:
- a spinnable medium with one or more internal chambers capable of containing one or more reagents;
- a composite reagent in one or more of the internal chambers, the composite reagent further comprising a magnetic component;
- a rotating mechanism capable of turning the spinnable medium;
- and
- a reading mechanism capable of measuring the magnetic component at one or more regions of the spinnable medium.
A method of characterizing reactions in a spinnable medium, comprising:
- placing a composite reagent into a reaction chamber within a spinnable medium, the composite reagent further comprising a tethered component with a bond to a second magnetic component;
- adding to the reaction chamber a target reagent that may react with the tethered component and displace the second magnetic component;
- operating the spinnable medium to facilitate transfer of the second magnetic component to an output chamber if it is displaced;
- measuring the second magnetic component;
- and
- characterizing the reaction of the target reagent and the tethered component according to the measurement of the second magnetic component.
A method of regulating the flow of fluids in a spinnable medium, comprising:
- inserting a magnetic material into one or more valve areas that separate one or more channels capable of carrying fluids in a spinnable medium;
- selectively introducing a magnetic field gradient in the vicinity of one or more of the valve areas to displace the magnetic material associated with one or more of the valve areas;
- opening a connection between one or more of the channels responsive to the displacement of the magnetic material;
- and
- rotating the spinnable medium thereby causing one or more fluids to flow through the valve areas under the influence of centrifugal force.
An apparatus for characterizing reactions comprising:
- means for placing a composite reagent into a reaction chamber within a spinnable medium, the composite reagent further comprising a tethered component with a bond to a second magnetic component;
- means for adding to the reaction chamber a target reagent that may react with the tethered component and displace the second magnetic component;
- means for operating the spinnable medium to facilitate transfer of the second magnetic component to an output chamber if it is displaced;
- and
- means for measuring the second magnetic component.
Dependencies are inferred from the claim text.