Cell line designated KT-1 established from tongue epithelial and use thereof
AssigneeNational Food Research Institute
InventorsTetsuya Ookura, Keiko Kawamoto, Akihiro Hino
Life of this patent
Estimating the term…
Abstract
A cell line KT-1 isolated from mouse tongue epithelium using high-level expression of integrin β1 as the indicator and established by a long time culture, and which expresses a taste receptor; a taste sensor comprising the cell line KT-1; the use of the cell line KT-1 to search for a factor which induces differentiation of taste cells, a substance which controls expression of taste receptors, a novel taste substance, a taste-modifying substance and a substance which aids in taste-suppressed state.
Claims17
A cell line KT-1 isolated from mouse tongue epithelium using high-level expression of integrin β1 as the indicator and established by a long-term culture, and which expresses a taste receptor.
A cell line KT-1 transformed by cDNA transfection of a taste receptor which is not expressed in cell line KT-1, and a ligand for which is known.
A cell line KT-1 transformed by cDNA trasnfection of a taste receptor which is not expressed in cell line KT-1, and ligand for which is unknown.
Dependencies are inferred from the claim text.