Abuse-proofed oral dosage form
OwnerJohannes Bartholomaus, Heinrich Kugelmanninventors
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Abstract
The present invention relates to an abuse-proofed oral dosage form with controlled release of (1R,2R)-3(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol for once daily administration, characterised in that it comprises the active ingredient and/or one or more of the pharmaceutically acceptable salts thereof (A), at least one synthetic or natural polymer (C), delayed-release auxiliary substances, optionally physiologically acceptable auxiliary substances (B) and optionally a wax (D), component (C) or (D) in each case exhibiting a breaking strength of at least 500 N, preferably of at least 1000 N.
Claims21
An abuse-proofed, oral dosage form with controlled release of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol for once daily administration, characterised in that it comprises the active ingredient and/or at least one of the pharmaceutically acceptable salts or derivatives thereof (A), at least one synthetic or natural polymer (C), optionally delayed-release matrix auxiliary substances, optionally physiologically acceptable auxiliary substances (B), optionally a wax (D) and optionally at least one delayed-release coating, component (C) or (D) in each case exhibiting a breaking strength of at least 500 N, preferably of 1000 N.
Dependencies are inferred from the claim text.