Treatment of conditions through modulation of the autonomic nervous system
AssigneePalo Alto Investors
InventorsAnthony Yun, Patrick Lee
Life of this patent
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Abstract
Methods are provided for treating a subject for a condition by modulating at least a portion of the subject's autonomic nervous system. In accordance with certain embodiments of the subject methods, at least a portion of a subject's autonomic nervous system is electrically or pharmacologically modulated in a manner that is effective to treat the subject for the condition. The subject methods find use in the treatment of a variety of different conditions, where such conditions include various disease conditions. Also provided are systems and kits for use in practicing the subject methods.
Claims25
A method of treating a subject for a condition comprising electrically modulating at least a portion of said subject's autonomic nervous system to increase the parasympathetic activity/sympathetic activity ratio in a manner effective to treat said subject for a condition chosen from the group of:
- cardiovascular conditions;
- neurodegenerative conditions;
- neuroinflammatory;
- orthopedic inflammatory conditions;
- lymphoproliferative conditions;
- autoimmune conditions;
- inflammatory conditions;
- infectious diseases;
- pulmonary conditions;
- transplant-related conditions;
- gastrointestinal conditions;
- endocrine;
- genitourinary conditions;
- skin conditions;
- aging associated conditions;
- neurologic conditions;
- pediatric conditions;
- Th-2 dominant conditions;
- conditions, including diseases, that cause hypoxia, hypercarbia, hypercapnia, acidosis, acidemia;
- OB-GYN conditions;
- sudden death syndromes, menstrual related disorders;
- peripartum and pregnancy related conditions;
- fibrosis;
- post-operative recovery conditions;
- post-procedural recovery conditions;
- chronic pain;
- trauma;
- hospitalization;
- glaucoma;
- male infertility;
- disorders of thermoregulation;
- respiratory sinus arrhythmia;
- VQ mismatch;
- and fibromyalgia.
21-51. (canceled)
A method of treating a subject for a condition comprising pharmacologically modulating at least a portion of said subject's autonomic nervous system to increase the parasympathetic activity/sympathetic activity ratio in a manner effective to treat said subject for a condition chosen from the group of:
- cardiovascular conditions;
- neurodegenerative conditions;
- neuroinflammatory;
- orthopedic inflammatory conditions;
- lymphoproliferative conditions;
- autoimmune conditions;
- inflammatory conditions;
- infectious diseases;
- pulmonary conditions;
- transplant-related conditions;
- gastrointestinal conditions;
- endocrine;
- genitourinary conditions;
- skin conditions;
- aging associated conditions;
- neurologic conditions;
- pediatric conditions;
- Th-2 dominant conditions;
- conditions, including diseases, that cause hypoxia, hypercarbia, hypercapnia, acidosis, acidemia;
- OB-GYN conditions;
- sudden death syndromes, menstrual related disorders;
- peripartum and pregnancy related conditions;
- fibrosis;
- post-operative recovery conditions;
- post-procedural recovery conditions;
- chronic pain;
- trauma;
- hospitalization;
- glaucoma;
- male infertility;
- disorders of thermoregulation;
- respiratory sinus arrhythmia;
- VQ mismatch;
- and fibromyalgia.
53-112. (canceled)
114-116. (canceled)
Dependencies are inferred from the claim text.