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AssigneeAlza Corporation
InventorsAndrew Lam, Padmaja Shivanand, Atul Ayer, Zahedeh Hatamkhany, Suneel Gupta, Diane Guinta, Carol Christopher, Samuel Saks, Lawrence Hamel, Jeri Wright, Richard Weyers
Estimating the term…
Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additionally comprise an immediate-release dose of drug.
1-34. (canceled)
A method comprising administering a composition that comprises a CNS-acting drug and a pharmaceutically acceptable carrier to a patient in a manner that achieves a substantially ascending plasma drug concentration over an extended time period following said administration.
A method for treating a patient comprising selecting a patient in a clinical situation where therapeutic effectiveness of an administered drug decreases at time periods before the end of the intended therapy period and administering a pharmaceutically acceptable composition and a pharmaceutically acceptable carrier to said patient in a manner that achieves a substantially ascending plasma drug concentration over a time period of about 8 hours following said administration.
Dependencies are inferred from the claim text.