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US 2005/0238542 A1Published application
Pins for spotting nucleic acids
AssigneeApplera Corporation
InventorsJulio Focaracci, Tony Yan
Life of this patent
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Abstract
The present application relates to an apparatus and method for pins for spotting nucleic acids.
Claims26
A pin for spotting nucleic acids, the pin comprising:
- a substantially pointed tip portion,
- wherein the tip portion has a pin angle that substantially corresponds to a draft angle of a well for holding fluid containing the nucleic acids.
A head for spotting nucleic acids, the head comprising:
- a plurality of pins, wherein each pin comprises a substantially pointed tip portion, wherein each tip portion has a pin angle that substantially corresponds to a draft angle of a well for holding fluid containing the nucleic acids.
A system for microarray spotting, the system comprising:
- at least one spotting pin comprising a substantially pointed tip portion;
- and
- at least one well, the at least one well defining a well draft angle,
- wherein the tip portion has a pin angle that substantially corresponds to a draft angle of a well for holding fluid containing the nucleic acids.
1 more element
A method for spotting a microarray, the method comprising:
- increasing nucleic acid transfer to a substrate;
- substantially preventing a spotting pin from contacting a side of a well containing the nucleic acid fluid by providing a substantially pointed tip portion on the spotting pin having a pin angle that substantially corresponds to a draft angle of the well.
A system for microarray spotting, the system comprising:
- means for spotting;
- wherein the means for spotting substantially prevents a nucleic acid from providing surface tension with a side of a well.
Dependencies are inferred from the claim text.