Method of screening remedy for renal failure
AssigneeYamanouchi Pharmaceutical Co., Ltd.
InventorsKentaro Enjo, Sadao Kuromitsu
Life of this patent
Estimating the term…
Abstract
A screening tool and a convenient screening method for obtaining a renal failure treating agent, and a pharmaceutical composition for treating renal failure and a production method thereof are disclosed. The aforementioned screening tool is a G protein coupling type receptor FGK which is a polypeptide capable of activating CTGF promoter, a functionally equivalent modified substance thereof or a homologous polypeptide, or a cell expressing the aforementioned polypeptide. The screening method is a method which employs inhibition of the aforementioned polypeptide as the index.
Claims12
A screening tool for an agent for treating renal failure, which is a polypeptide consisting of the amino acid sequence represented by SEQ ID NO:2, or a polypeptide comprising an amino acid sequence represented by SEQ ID NO:2 in which from 1 to 10 amino acids are deleted, substituted and/or inserted and which is capable of activating CTGF promoter.
Dependencies are inferred from the claim text.