Quadruplex stabilizer
AssigneeAcademia Sinica
InventorsTa-Chau Chang, Cheng-Chung Chang, Jin-Yi Wu
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AssigneeAcademia Sinica
InventorsTa-Chau Chang, Cheng-Chung Chang, Jin-Yi Wu
Estimating the term…
This invention relates to carbazole compounds of the following formula: In the above formula, each of rings A and B, independently, is heteroaryl containing at least one nitrogen atom; each of X and Y, independently, is CH or N; each of R1-R6, independently, is H, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C8 cycloalkyl, C3-C8 heterocycloalkyl, aryl, heteroaryl, OH, C1-C6 alkoxy, aryloxy, heteroaryloxy, NH2, C1-C6 alkylamino, C1-C12 dialkylamino, arylamino, diarylamino, or halogen; R7 is H, C1-C8 alkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C8 cycloalkyl, C3-C8 heterocycloalkyl, aryl, heteroaryl; and each of m and n, independently, is 1, 2, or 3.
A compound of the formula:
A method for stabilizing a G-quadruplex of a telomere, comprising contacting a telomere with a compound of the formula:
Dependencies are inferred from the claim text.