High-efficiency fusogenic vesicles, methods of producing them, and pharmaceutical compositions containing them
AssigneePevion Biotech Ltd.
InventorsSonia Vadrucci, Joseph Brunner, Rinaldo Zubriggen
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Abstract
The present invention relates to novel fusogenic vesicles as highly efficient and versatile encapsulation systems for delivering a substance of choice, such as nucleic acids, proteins, peptides, antigens, pharmaceutical drugs and cosmetic agents to cells and tissues.
Claims38
A fusogenic vesicle comprising virosomal and liposomal lipids, capable of encapsulating at least one therapeutic or immunologically active substance, said fusogenic vesicle comprising fusion proteins or peptides with distinct fusion characteristics.
A method for preparing a fusogenic vesicle encapsulating at least one therapeutic or immunologically active substance, comprising fusing liposomes encapsulating at least one therapeutic or immunologically active substance with virosomes having fusion proteins with distinct fusion characteristics.
A method of encapsulating at least one therapeutic or immunologically active substance in a fusogenic vesicle comprising fusing liposomes encapsulating at least one therapeutic or immunologically active substance with virosomes having fusion proteins with distinct fusion characteristics.
Dependencies are inferred from the claim text.