US 2005/0038415 A1 · Method and apparatus for the treatment of obesity

Abstract

The present invention includes methods and materials for manipulating the sense of satiety developed from the gastrointestinal transit of a substance in a mammal, whether the substance be a food or drug compound. The method involves administering a therapeutically effective amount, by a direct delivery route, of a pharmaceutically acceptable formulation comprising nutrients and pharmacological agents to the mammal's gastrointestinal tract. The present system is designed to maximize satiety feedback from normal intestinal sensors by small amounts of nutrients or nutrient derivatives, in essence, to “fool” body sensors that are not usually in contact with nutrients unless very large amounts are ingested.

Claims40

Dependent claims

A method of modulating satiety in a subject, the method comprising:

implanting in a subject, at an implantation site, an active agent delivery system comprising a pump and a formulation, the formulation comprising an active agent selected from the group consisting of nutrients and pharmacological agents, wherein the formulation comprises a therapeutically effective amount of the active agent sufficient for inducing or promoting a feeling of satiety in the subject, and delivering the formulation from the active agent delivery system to the subject whereby the active agent enters the gastrointestinal system, whereby the active agent is present at the site of action within the gastrointestinal tract in an amount sufficient to modulate satiety.

Dependencies are inferred from the claim text.

Facts

Application

10/890,304Filed 12 Jul 2004

Priority

6 Aug 2003

Published

17 Feb 2005

Term ends

Not estimatedThe source records don’t support an estimate.

Classification16 codes

A61M 5/14276
Adapted to be carried by the patient, e.g. portable on the body: specially adapted for implantation
A23L 33/175
Amino acids, peptides or proteins: amino acids
A23L 33/30
Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof: dietetic or nutritional methods, e.g. for losing weight
A61F 5/0003
Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices: apparatus for the treatment of…

Method and apparatus for the treatment of obesity

Life of this patent

Method and apparatus for the treatment of obesity

Life of this patent

Abstract

Claims40