Use of dipyridamole, acetylsalicylic acid and an angiotensin II antagonist for treatment and prevention of vascular events

A method for preventing or treating indications (B) selected from

• pulmonary embolism, retinal vascular accident, deep vein thrombosis, peripheral arterial occlusion, transient ischemic attack (TIA), ischaemic peripheral circulatory disorders, myocardial ischaemia (angina), thrombotic thrombocytopenic purpura, or progression of cardiac insufficiency after myocardial infarction,
• said method comprising administering to a patient in need of such treatment an effective amount of a pharmaceutical composition comprising dipyridamole or a pharmaceutically acceptable salt thereof in combination with acetylsalicylic acid and an angiotensin II antagonist.

A method for preventing or treating indications (C), which can be positively influenced by organoprotective, tissue-protective and vasculoprotective effects of the drugs used, selected from

• renoprotection, left ventricular hypertrophy, or vascular thickening,
• said method comprising administering to a patient in need of such treatment an effective amount of a pharmaceutical composition comprising dipyridamole or a pharmaceutically acceptable salt thereof in combination with acetylsalicylic acid and an angiotensin II antagonist.

A method for preventing or treating indications (D) selected from

• obstructive airway diseases, chronic obstructive pulmonary disease, emphysema, asthma, cystic fibrosis, interstitial lung disease, lung cancer, pulmonary vascular disease, increased resistance to airflow during forced expiration, adult respiratory distress syndrome (ARDS), reduced proliferative capacity of the epithelium in lung and breast cancer, sepsis syndrome, lung injury, chest trauma, shock, burns, fat embolia, cardiopulmonary bypass, O2 toxicity, haemorhagic pancreatitis, interstitial and bronchoalveolar inflammation, proliferation of epithelial and interstitial cells, collagen accumulation or fibrosis,
• said method comprising administering to a patient in need of such treatment an effective amount of a pharmaceutical composition comprising dipyridamole or a pharmaceutically acceptable salt thereof in combination with acetylsalicylic acid and an angiotensin II antagonist.

A pharmaceutical composition comprising dipyridamole or a pharmaceutically acceptable salt thereof, acetyl salicylic acid and an angiotensin II antagonist for simultaneous, separate or sequential use.